| 2021-12-31 | Thomas Harris | Stabbing | 1500 block of Beta Drive |
| 2021-12-31 | Sean Waldon | Shooting | 9400 block of Miriam Avenue |
| 2021-12-29 | Kimberly Lynn Oshia | Shooting | 1100 block of St. Patrice Lane |
| 2021-12-24 | Derrick Brookfield | Shooting | Martin Luther King Drive and Ogden Avenue |
| 2021-12-12 | George Hollins Jr. | Police | 2000 block of Coleridge Drive |
| 2021-12-12 | Jeremi Moore | Police | Tiffin and South Marguerite avenues |
| 2021-12-01 | Jaivyon Hudson | Shooting | 2700 block of Solway Avenue |
| 2021-11-10 | Melvin McCombs | Vehicular | 11800 block of West Florissant Avenue |
| 2021-10-24 | Tommy Byrd | Shooting | 8717 College Avenue |
| 2021-10-24 | Marilyn Taylor | Shooting | 2997 Santiago Drive |
| 2021-10-07 | Eli Taylor | Beating | 11400 block of Latonka Trail |
| 2021-09-26 | Lester Robinson | Shooting | 1700 block of Barbados Lane |
| 2021-09-23 | Larry Drummond | Stabbing | 3900 block of Lada Avenue |
| 2021-09-18 | Robert Smith | Shooting | 10300 block of Royal Drive. |
| 2021-09-14 | Brian McIntosh | Shooting | 4700 Highland Avenue |
| 2021-09-13 | Marnay Haynes | Shooting | 9900 block of Glen Owen Drive |
| 2021-09-11 | Arion J. Burse | Shooting | 6200 block of Chatham Avenue |
| 2021-09-01 | Callion Barnes | Shooting | 10000 block of Duke Drive |
| 2021-08-26 | Robert Crutchfield | Shooting | 7100 block of Glenmore Avenue |
| 2021-08-14 | Mya Ward | Shooting | 200 block of Meadowcrest Drive |
| 2021-08-14 | Shaunta Johnson | Shooting | 200 block of Meadowcrest Drive |
| 2021-08-13 | Brian Vazquez | Shooting | 1400 block of grant road |
| 2021-08-06 | Adrian Burns | Shooting | 1800 Bahama Court |
| 2021-08-06 | Bhritnay Taylor | Shooting | 1800 Bahama Court |
| 2021-08-03 | Nevaeh Smallwood | Shooting | 10200 Lynncrest Court |
| 2021-08-02 | Kendrick Stayton | Shooting | 1100 North Florissant Road |
| 2021-07-31 | Charlisa Turner | Shooting | 2100 Old Manor Road |
| 2021-07-27 | Alexi Hawkins | Vehicular | Gravois Road and Winternight Lane |
| 2021-07-24 | Gregg Price | Shooting | 8600 block of Trumbell Avenue |
| 2021-07-23 | Cameron Biedscheid | Shooting | 6800 Champaigne Drive |
| 2021-07-20 | Jerrard Shegog | Shooting | 11100 block of East Pasture Drive |
| 2021-07-16 | Austin Phillips | Shooting | Highmont Drive and Gage Drive |
| 2021-07-10 | Norman Green | Shooting | 8500 Scudder Avenue |
| 2021-07-08 | Emya Woods | Child | 1700 block of Parker Road |
| 2021-07-07 | Damon White | Shooting | 11800 block of Criterion Avenue |
| 2021-07-06 | Darryl Franks | Shooting | 11900 block of El Sabedo Drive |
| 2021-07-06 | Kimmy Goodson | Shooting | 2100 block of Chambers Road |
| 2021-07-03 | Malachi Maclin | Shooting | 80 W County Center Dr |
| 2021-06-30 | Devonte Carter Jr. | Unspecified | 5400 block of Hamilton Avenue |
| 2021-06-27 | Jamez Prewitt | Shooting | 1300 block of Sharondale Circle |
| 2021-06-18 | Demetrius Carbon | Shooting | 6007 Nevis Court |
| 2021-06-18 | Johnesia Murry | Shooting | 11400 Bellefontaine Road |
| 2021-06-16 | Ervin Costello | Shooting | 8400 Latty Avenue |
| 2021-06-11 | William Bellamy | Shooting | 705 Waterford Drive |
| 2021-06-06 | Allen Waller | Shooting | 400 Macdougall Drive |
| 2021-06-02 | Blessed Adams | Child | 2700 block of McKelvey Road |
| 2021-05-31 | Alex Mitchell | Shooting | 2800 Blackforest Drive |
| 2021-05-29 | Kyree Shakur Smith | Shooting | 10466 West Florissant Avenue |
| 2021-05-28 | Kerven Moline | Shooting | 7000 block of Vernon Avenue |
| 2021-05-27 | Richard Hoelscher | Stabbing | 12000 Riverview Drive |
| 2021-05-25 | Levante Falls | Shooting | 7848 Olive Boulevard |
| 2021-05-15 | Sergei Zacharev | Shooting | 8700 block of Eager Road |
| 2021-05-15 | Barbara Goodkin | Shooting | 8200 block of Delmar Boulevard |
| 2021-05-09 | Terrion Alexander | Shooting | 7200 block of Woodstead Court |
| 2021-05-07 | Montrez Hughes | Shooting | 5500 block of Mable Avenue |
| 2021-05-07 | Eddie Wilkerson | Shooting | 5500 block of Mable Avenue |
| 2021-05-06 | Myron Goodwin | Shooting | 8400 block of Plaza Rock Court |
| 2021-05-06 | Michael Goodwin | Shooting | 8400 block of Plaza Rock Court |
| 2021-04-30 | Antonia Huey | Shooting | 166 block of Norlakes Drive |
| 2021-04-20 | Antonio Green | Shooting | 1100 block of Scott Avenue |
| 2021-04-19 | Alfonso Watts | Shooting | 10800 block of Hallstead Drive |
| 2021-04-14 | Marshall Frenchie | Shooting | 8431 Lucas and Hunt Road |
| 2021-04-14 | Marquise Foston | Shooting | 2300 block of Chambers Road |
| 2021-04-06 | Elijha Walton | Shooting | 2900 block of Canfield Drive |
| 2021-04-06 | Damaurion Williams | Shooting | 1200 Territory Court |
| 2021-04-03 | Sean Moore | Shooting | 3800 block of Louisiana Avenue |
| 2021-03-31 | Sharif Khan | Shooting | 700 block of West Canterbury |
| 2021-03-30 | Christian Stewart | Shooting | 11800 block of Iguana Terrace Drive |
| 2021-03-30 | Courtland Crump | Shooting | 8600 block of Stella Avenue |
| 2021-03-24 | Tianna Baker | Shooting | 2400 block of Akins Drive |
| 2021-03-12 | Tradena Peters | Shooting | EB I-270 between Old Halls Ferry and New Halls Ferry roads |
| 2021-03-04 | Kaylee Brooks | Shooting | 4855 Lockwig Trail |
| 2021-03-04 | Kayden Johnson | Shooting | 4855 Lockwig Trail |
| 2021-03-04 | Roseann Williams McCulley | Shooting | 4855 Lockwig Trail |
| 2021-02-26 | Cortney Smith | Shooting | 11600 block of Criterion Avenue |
| 2021-02-17 | Darren Santiago | Shooting | 7400 block of West Florissant Avenue |
| 2021-02-10 | Ardie Knighten | Beating | 12031 Lackland Road |
| 2021-02-02 | Jamell Killiebrew | Shooting | 9800 block of Omega Drive |
| 2021-02-01 | Kevin McCanery | Shooting | 8700 block of Jennings Station Road |
| 2021-01-29 | Demetrius Gregory | Shooting | 7500 block of Liberty Avenue |
| 2021-01-26 | Crystal Lynn McCandless | Stabbing | 2112 Charlack Avenue |
| 2021-01-26 | Brantley Tate | Shooting | 2700 block of Mullanphy Road |
| 2021-01-25 | Richard Gomillia | Shooting | 7200 block of Woodstead Court |
| 2021-01-22 | Tyrique Hickman | Unspecified | 12600 block of Columbia Bottom Road |
| 2021-01-20 | Michael Hayes | Vehicular | Bellefontaine Road and Chain of Rocks Drive |
| 2021-01-19 | Trevon Wright | Shooting | 3675 Dunn Road |
| 2021-01-18 | Sharita Brooks | Shooting | 1600 block of Claudine Drive |
| 2021-01-12 | Ronald Ross | Shooting | 200 block of Chambers Road |
| 2021-01-10 | Emon Saunders | Shooting | 1700 block of El Sabado Drive |
| 2021-01-08 | Denise Edwards | Shooting | 11000 block of Lilac Avenue |
| 2021-01-01 | Rashon Butler | Shooting | 300 block of South Dellwood Avenue |